“International Medical Service in Egypt.”

ASOT (Anti-Streptolysin O titer)

fection of the upper respiratory tract by Group A streptococci in humans may be followed by the development of glomerulonephritis, acute endocarditis, Chorea and acute rheumatic fever. These diseases can later lead to damage of the heart or the kidneys.

Early diagnosis, efficient treatment and monitoring of patients can reduce these risks.

Several metabolites of β-hemolytic streptococci are exogenous toxins for the human body that can induce immunological defense reactions with the production of several antibodies, the most clinically significant of which is against streptolysin O exotoxin (Oxygen-labile).

The use of standard conventional latex agglutination techniques in the estimation of the level of ASO antibodies in sera of humans can only provide clinicians with qualitative (positive/negative) or semi-quantitative values.

Alfa Laboratories have introduced the Immunoturbidimetry technique as an automated assaythat can provide an accurate quantitative estimation (titration) of anti-streptolysin O antibodies (ASO) in sera of patients and help as a useful method for diagnosis. It can also indicate either the development of successful treatment or that the antigen stimulus is still persisting even if the clinical signs of infection have already disappeared.

Useful tip: Appropriate evaluation of streptococcal infection is possible only if the test is repeated after one or two weeks to obtain useful data about the clinical course of the disease.

Reference Range:

For adults: < 200 IU/mL

For children: < 150 IU/mL

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